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Lemierre's Syndrome

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Lemierre's Syndrome
We describe a 32-year-old woman who had temperatures increasing over 7 days from 100.7°F to 104.0°F. She had an upper respiratory infection and swelling of the left side of the neck. She was diagnosed with Lemierre's syndrome.

Lemierre's syndrome (postanginal septicemia) was first described in 1936. The "angina" in this syndrome refers to an acute pharyngeal infection with the anaerobe Fusobacterium necrophorum. The acute pharyngitis is followed by a septic thrombophlebitis of the internal jugular vein and dissemination of the infection to multiple sites distant from the pharynx. In the preantibiotic era, Lemierre's syndrome was often fatal.

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