25-Hydroxyvitamin D Deficiency and Mortality in Severe Sepsis

Conclusion

Patients deficient in vitamin D within 30 days of hospital admission for severe sepsis or septic shock had increased all-cause 30-day mortality. Risk of mortality may be potentially modifiable by ensuring adequate levels of 25-hydroxyvitamin D. Further evaluation in a larger sample of patients or through randomized controlled trials is necessary to further explore our results.