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Shark Cartilage: Biological Actions, Employment and Prospects

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Dried shark cartilage powder is a natural product, which is attributed to different biological actions and has been widely used. In this paper, a literature review was performed. Shark cartilage obviously has particular structural characteristics that differentiate it from cartilage of higher vertebrates and man. They have been under study and tested of basic and inhibitory actions of angiogenesis. In the last 3 years it has been shown that shark cartilage glycosaminoglycans show a growth modulating activity and development of neurons in tissue culture. Other biological actions investigated were: anti-inflammatory, ant mutagenic, and activating the immune response antilipemiante action. Cuba is recognized among the first to use complementary therapy in refractory advanced cancer. However, their use is necessary for therapeutic purposes are based clinical trials, which have not been conclusive so far.
Traditional and Natural Medicine (MTN) has achieved growing recognition at the international level and is situated with its own personality, in the fight against multiple diseases, both in combined form with the procedures of conventional therapy alone as. Its popular use is widespread and suffice it to say that it has been reported that in the year 1997.42 % of Americans used these medical therapies, also called alternatives.

Dried shark cartilage powder (CT) is a natural product, which, in addition to nutritional supplement, it is granted a set of beneficial properties in the prophylaxis and treatment of various diseases and especially therapy. Shark cartilage as a treatment option in advanced cancer refractory to conventional on co- specific procedures. preliminary results in 114 patients [ Scientific Communication ] ISMM " Dr. Luis Diaz Soto", Havana, Cuba, 1993 ). It is produced in different countries, including Cuba, and is recognized to have been one of the first countries to use in the treatment of patients with advanced cancer.

Composition and shark cartilage structured

The CT, like other cartilage of animals and man, consists of specialized cells (chondrocytes, chondroblasts and chondroclasts) an extracellular matrix and an inorganic phase Extracellular matrix constituent components fibrillar and non-fibrillar.

Component is fibrillar collagen protein characterized by its amino acid composition and structural organization of the polypeptide series, which are arranged in three chains with a helical structure, and surround a central region that forms a long and rigid cylinder. The helical chains show a glycine residue at every third position in the amino acid series components.8 9 In higher vertebrates, cartilage comprises predominantly collagen type II (90 %) and type I (10 %). In the CT has been shown that from the backbone is composed of type II collagen in 66 % and 33 % type I collagen, which constitutes a remarkable diferencia10 JW Alencar11 and others have reported the isolation and identification of the lipid composition of a commercial sample detected in a component of CT, which is not observed in the higher vertebrate cartilage and man. Recently been demonstrated polymorphism collagen in cartilage of invertebrates.
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