Our Primary Objective Is the Development of Stem Cell Therapies
Benefits: Stem Cell Therapy
There is about a 40% to 60% overall success rate in the use of stem cell therapy in both India and around the world. However, success rates vary depending on the disease being treated. We have had NO negative effects with any of our patients from any of our performed procedures. In our experience, the worst case scenario is one where our treatment does not have any positive effect on the patient.
The potential application of stem cells is making cells and tissues for medical therapies. Today, donated organs and tissues are often used to replace those that are diseased or destroyed. Unfortunately, the number of people needing a transplant far exceeds the number of organs available for transplantation but with the application of Stem Cells given the ray of hope to improve the one's quality of life and following results are observed with passage of time:
1) Repair injuries to the heart muscle of heart attack victims
The damaged heart can progress through various stages including inflammation, heart cell injury and death, scar formation, compensation by adjacent tissue and perhaps gradual degeneration towards congestive heart failure. Until recently, non-invasive methods of restoring heart function included hyperbaric oxygen and external counterpulsation. Currently, mesenchymal stem cells and growth factors are being considered that would help repair damaged blood vessels as well as restore heart muscle cell (cardiomyocyte) function in the injured areas of the heart.
2) Reduce the clinical symptoms of Parkinson's disease.
Parkinson's disease is a chronic, progressive neurodegenerative disorder characterized by tremor, rigidity of limbs and body, slowness of movement and loss of balance and coordination. The mesenchymal stem cells derived from sources of stem cells have been shown to reduce Parkinson symptoms in laboratory animals and several human subjects without any detrimental side effects associated with stem cell sources.
3) Improve the outcome of cancer patients.
The hematopoietic stem/progenitor cells restore blood, bone marrow and immune function after radiation or chemotherapy. In addition, stem cells themselves may fight against cancers. Neural stem cells have been found to release cytokines and growth factors that inhibit the proliferation of glioma cells by 28-87%. Also, stem/progenitor cells from human umbilical cord blood have been found to prolong the life of mouse models for prostate cancer.
4) Improve the quality of life in patients with Multiple Sclerosis.
Multiple Sclerosis (MS) is an inflammatory, autoimmune, demyelinating disease of the central nervous system that destroys myelin, oligodendrocytes, and axons. Initial symptoms may include extreme fatigue, vertigo, optic neuritis, and numbness in the extremities. Most patients experience relapsing-remitting episodes that over time can lead to progressive neurological deterioration. Current therapies for MS are designed to delay disease progression by immuno-modulation or immunosuppression. Until recently, the slowing accumulating neurological damage has remained mostly irreversible. Today, there is increased optimism about slowing and perhaps reversing the disease with a comprehensive program that includes stem cell therapies along with therapies that improve blood circulation, myelin regeneration, mitochondrial energy production and dietary, anti-inflammatory, antimicrobial and antioxidant factors.
5) Improve outcome for children with cerebral palsy.
Brain imaging scans of cerebral palsy children show hypoperfusion, (a lack of blood flow) in various regions of the brain, including the thalamus, cerebellum and/or basal ganglia. Umbilical cord derived stem cells have the ability to help repair the entire system by
stimulating angiogenesis, the development of new blood vessels to the damaged areas,
repairing the white matter through the production of glial cells
repairing the grey matter through the stimulation of growth factors and direct or indirect stimulation of neurogenesis,
dividing into new neurons once the oxygen and nutrient supply can support them,
strengthening of muscle tissue and
improving immune function.
6) Improve outcome for acute and chronic stroke patients.
Ischemic stroke often results from a blockage in the blood supply to an area of the brain. The tissue most affected quickly dies off, followed by increasing dysfunction in the surrounding tissue from secondary causes such as inflammation, edema, and oxidative stress.
A comprehensive program of rehabilitation that includes stem cell therapy is advised for both acute and chronic stroke patients. Current programs in hyperbaric oxygen therapy, external counterpulsation, neuroprotective intravenous therapies and physical therapy are recommended.
There is about a 40% to 60% overall success rate in the use of stem cell therapy in both India and around the world. However, success rates vary depending on the disease being treated. We have had NO negative effects with any of our patients from any of our performed procedures. In our experience, the worst case scenario is one where our treatment does not have any positive effect on the patient.
The potential application of stem cells is making cells and tissues for medical therapies. Today, donated organs and tissues are often used to replace those that are diseased or destroyed. Unfortunately, the number of people needing a transplant far exceeds the number of organs available for transplantation but with the application of Stem Cells given the ray of hope to improve the one's quality of life and following results are observed with passage of time:
1) Repair injuries to the heart muscle of heart attack victims
The damaged heart can progress through various stages including inflammation, heart cell injury and death, scar formation, compensation by adjacent tissue and perhaps gradual degeneration towards congestive heart failure. Until recently, non-invasive methods of restoring heart function included hyperbaric oxygen and external counterpulsation. Currently, mesenchymal stem cells and growth factors are being considered that would help repair damaged blood vessels as well as restore heart muscle cell (cardiomyocyte) function in the injured areas of the heart.
2) Reduce the clinical symptoms of Parkinson's disease.
Parkinson's disease is a chronic, progressive neurodegenerative disorder characterized by tremor, rigidity of limbs and body, slowness of movement and loss of balance and coordination. The mesenchymal stem cells derived from sources of stem cells have been shown to reduce Parkinson symptoms in laboratory animals and several human subjects without any detrimental side effects associated with stem cell sources.
3) Improve the outcome of cancer patients.
The hematopoietic stem/progenitor cells restore blood, bone marrow and immune function after radiation or chemotherapy. In addition, stem cells themselves may fight against cancers. Neural stem cells have been found to release cytokines and growth factors that inhibit the proliferation of glioma cells by 28-87%. Also, stem/progenitor cells from human umbilical cord blood have been found to prolong the life of mouse models for prostate cancer.
4) Improve the quality of life in patients with Multiple Sclerosis.
Multiple Sclerosis (MS) is an inflammatory, autoimmune, demyelinating disease of the central nervous system that destroys myelin, oligodendrocytes, and axons. Initial symptoms may include extreme fatigue, vertigo, optic neuritis, and numbness in the extremities. Most patients experience relapsing-remitting episodes that over time can lead to progressive neurological deterioration. Current therapies for MS are designed to delay disease progression by immuno-modulation or immunosuppression. Until recently, the slowing accumulating neurological damage has remained mostly irreversible. Today, there is increased optimism about slowing and perhaps reversing the disease with a comprehensive program that includes stem cell therapies along with therapies that improve blood circulation, myelin regeneration, mitochondrial energy production and dietary, anti-inflammatory, antimicrobial and antioxidant factors.
5) Improve outcome for children with cerebral palsy.
Brain imaging scans of cerebral palsy children show hypoperfusion, (a lack of blood flow) in various regions of the brain, including the thalamus, cerebellum and/or basal ganglia. Umbilical cord derived stem cells have the ability to help repair the entire system by
stimulating angiogenesis, the development of new blood vessels to the damaged areas,
repairing the white matter through the production of glial cells
repairing the grey matter through the stimulation of growth factors and direct or indirect stimulation of neurogenesis,
dividing into new neurons once the oxygen and nutrient supply can support them,
strengthening of muscle tissue and
improving immune function.
6) Improve outcome for acute and chronic stroke patients.
Ischemic stroke often results from a blockage in the blood supply to an area of the brain. The tissue most affected quickly dies off, followed by increasing dysfunction in the surrounding tissue from secondary causes such as inflammation, edema, and oxidative stress.
A comprehensive program of rehabilitation that includes stem cell therapy is advised for both acute and chronic stroke patients. Current programs in hyperbaric oxygen therapy, external counterpulsation, neuroprotective intravenous therapies and physical therapy are recommended.
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