Causes

• According to the American Cancer Society, hair, skin and nail changes during cancer treatment are often caused by certain chemotherapy drugs.
  
  

Symptoms

• You may begin to notice your nail beds darken or become brittle. It is also common to notice ridges or notice that nails appear to loosen. This can happen with both toenails and fingernails.
  
  

Solutions

• Nail creams are effective for nails that become brittle during cancer treatments. Also, the National Cancer Institute suggests using a frozen glove. A French study has shown that patients who have worn a frozen glove during intravenous chemotherapy treatments have reportedly experienced less damage to their skin and nails.
  
  

Warning

• If you suspect the onset of onychomadesis, make sure you are gentle with your hands and feet. You do not want to "rip" a toenail or fingernail off; even if it is loosened, removing it before it is ready can be very painful.
  
  

Tips

• Make sure you keep your feet protected at all times. Do not wear open-toe sandals or shoes, as these can put your toenail at risk.