Serum Homocysteine in Thyroiditis Treated With Levothyroxine
Serum Homocysteine in Thyroiditis Treated With Levothyroxine
Descriptive characteristics for the study groups and the control group are shown in Table 1.
The study groups and the controls did not differ in age and BMI.TSH levels of treated and non treated HT patients were similar to those of control subjects. FT4 concentrations of treated HT patients were significantly higher as compared with non treated HT and did not differ from controls (Figure 1). TPOAbs titers were higher in both groups of HT patients versus the healthy controls.Hcy levels were found to be significantly lower in treated HT patients as compared with healthy controls (Figure 2). In contrast, no significant difference was found between non treated HT and control group in Hcy level.
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Figure 1.
FT4 concentrations in non treated and treated HT and in controls.
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Figure 2.
Hcy levels in non treated and treated HT and in controls.
In treated HT females Hcy level was negatively correlated with age (p = 0.017289; r = -0.42). In contrast, correlation between Hcy and age was not found in non treated HT and in controls. No significant associations were found between Hcy and BMI, waist circumference, TSH, FT4, TPOAbs in all of HT patients and in healthy females. Furthermore, levels of TC, LDL, HDL and TAG did not differ between the study groups and the control group.
Results
Descriptive characteristics for the study groups and the control group are shown in Table 1.
The study groups and the controls did not differ in age and BMI.TSH levels of treated and non treated HT patients were similar to those of control subjects. FT4 concentrations of treated HT patients were significantly higher as compared with non treated HT and did not differ from controls (Figure 1). TPOAbs titers were higher in both groups of HT patients versus the healthy controls.Hcy levels were found to be significantly lower in treated HT patients as compared with healthy controls (Figure 2). In contrast, no significant difference was found between non treated HT and control group in Hcy level.
(Enlarge Image)
Figure 1.
FT4 concentrations in non treated and treated HT and in controls.
(Enlarge Image)
Figure 2.
Hcy levels in non treated and treated HT and in controls.
In treated HT females Hcy level was negatively correlated with age (p = 0.017289; r = -0.42). In contrast, correlation between Hcy and age was not found in non treated HT and in controls. No significant associations were found between Hcy and BMI, waist circumference, TSH, FT4, TPOAbs in all of HT patients and in healthy females. Furthermore, levels of TC, LDL, HDL and TAG did not differ between the study groups and the control group.
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