From Murderers to Lifeguard, WHO?—“SHARKâ€
Despite its fearsome reputation sharks could soon become lifesavers. Shark immune system is similar to the human antibody but has very special. According to scientists at La Trobe University in Melbourne, Australia, antibodies of these animals can potentially be used as a potential weapon to fight cancer and other diseases.
Antibodies are proteins in the blood that are responsible for fighting diseases. The immune system produces to defend the body from bacteria, viruses, or other foreign substances. Sharks have immune systems similar to humans but also possess an unusual type of antibodies capable of halting the progression of certain diseases. Australia investigated treatments may be useful in combating certain types of cancer, malaria and rheumatoid arthritis. Shark antibodies themselves are very small (the smallest of the animal kingdom), more robust chemically and biologically more stable than conventional antibodies. So calls are appropriate for targeted therapies. The interesting thing is that these antibodies continue to remain stable when placed in digestive enzymes. For example, one could develop new treatments of antibodies can be taken orally instead of being injected.
Professor Mick Foley who is leading the investigation the first step in the development of an antibody that can be taken orally (which therapeutic science has pursued for many years) is that it be able to survive the acidic conditions of the gastrointestinal tract.
"We can exposing shark antibodies to soaring temperatures and would disintegrate like conventional molecules but more interesting is that these antibodies continue to remain stable when placed in digestive enzymes€ said the researcher. €Shark These molecules appear to remain stable in the stomach and therefore already passed the first step in the development of this therapy," he added. This is not the first time recognized the potential of shark antibodies to combat diseases. But other practices that is being experienced in the world require shark first immunize it develops antibodies.
The antibodies could treat various diseases such as cancer, malaria and arthritis. The new technique requires no prior immunization; scientists therefore do not face the animal for immunization. As stated by Professor Foley, shark antibodies have also proved highly effective in combating the parasite that causes malaria. In a study conducted in 2004, scientists discovered that the shark antibody has a kind of long hook, like a finger, projecting from the surface and attaches to a pocket in the protein of malaria.
This process locks the molecular functions of the protein and prevents it invades human red blood cells.
€The goal now is to use these shark antibodies adhere to achieve anything we want like molecules of cancer cells or proteins that cause inflammation in rheumatoid arthritis. In this way we could use as treatments," Foley concluded. The analysis of these capabilities may one day give humans the same capabilities through the fabrication of devices designed based on the senses of the sharks. Recent studies indicate that sharks are highly intelligent, with advanced problem-solving skills, social complexity and a natural sense of curiosity. Using devices that detect neuronal activity, scientists developed rudimentary ways to interpret the thoughts and feelings of these animals.
Antibodies are proteins in the blood that are responsible for fighting diseases. The immune system produces to defend the body from bacteria, viruses, or other foreign substances. Sharks have immune systems similar to humans but also possess an unusual type of antibodies capable of halting the progression of certain diseases. Australia investigated treatments may be useful in combating certain types of cancer, malaria and rheumatoid arthritis. Shark antibodies themselves are very small (the smallest of the animal kingdom), more robust chemically and biologically more stable than conventional antibodies. So calls are appropriate for targeted therapies. The interesting thing is that these antibodies continue to remain stable when placed in digestive enzymes. For example, one could develop new treatments of antibodies can be taken orally instead of being injected.
Professor Mick Foley who is leading the investigation the first step in the development of an antibody that can be taken orally (which therapeutic science has pursued for many years) is that it be able to survive the acidic conditions of the gastrointestinal tract.
"We can exposing shark antibodies to soaring temperatures and would disintegrate like conventional molecules but more interesting is that these antibodies continue to remain stable when placed in digestive enzymes€ said the researcher. €Shark These molecules appear to remain stable in the stomach and therefore already passed the first step in the development of this therapy," he added. This is not the first time recognized the potential of shark antibodies to combat diseases. But other practices that is being experienced in the world require shark first immunize it develops antibodies.
The antibodies could treat various diseases such as cancer, malaria and arthritis. The new technique requires no prior immunization; scientists therefore do not face the animal for immunization. As stated by Professor Foley, shark antibodies have also proved highly effective in combating the parasite that causes malaria. In a study conducted in 2004, scientists discovered that the shark antibody has a kind of long hook, like a finger, projecting from the surface and attaches to a pocket in the protein of malaria.
This process locks the molecular functions of the protein and prevents it invades human red blood cells.
€The goal now is to use these shark antibodies adhere to achieve anything we want like molecules of cancer cells or proteins that cause inflammation in rheumatoid arthritis. In this way we could use as treatments," Foley concluded. The analysis of these capabilities may one day give humans the same capabilities through the fabrication of devices designed based on the senses of the sharks. Recent studies indicate that sharks are highly intelligent, with advanced problem-solving skills, social complexity and a natural sense of curiosity. Using devices that detect neuronal activity, scientists developed rudimentary ways to interpret the thoughts and feelings of these animals.
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