Guidance on the Effective Use of Upper GI Histopathology
Guidance on the Effective Use of Upper GI Histopathology
Our recommendations on what to biopsy and what not to biopsy during upper gastrointestinal endoscopy are summarised in Table 1. In brief, there are clear indications for endoscopic biopsy in evaluating mass lesions and investigating some inflammatory conditions, such as eosinophilic oesophagitis and coeliac disease, with increasing guidance available on optimal sites and biopsy numbers to maximise yield from histology. Outside these indications, it is important to consider whether biopsy of normal appearing or inflamed mucosa is likely to contribute to patient management in upper gastrointestinal disease.
Conclusions
Our recommendations on what to biopsy and what not to biopsy during upper gastrointestinal endoscopy are summarised in Table 1. In brief, there are clear indications for endoscopic biopsy in evaluating mass lesions and investigating some inflammatory conditions, such as eosinophilic oesophagitis and coeliac disease, with increasing guidance available on optimal sites and biopsy numbers to maximise yield from histology. Outside these indications, it is important to consider whether biopsy of normal appearing or inflamed mucosa is likely to contribute to patient management in upper gastrointestinal disease.
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