Laboratory Diagnosis of Hepatitis A
Laboratory Diagnosis of Hepatitis A
Hepatitis A virus (HAV) is a nonenveloped virus that belongs to the Hepatovirus genus in the Picornaviridae family. The viral genome consists of a linear, positive-sense, ssRNA that is approximately 7.5 kb in length. HAV demonstrates little antigenic variability, and isolates taken from different parts of the world belong to a single serotype. Acute infection is diagnosed by detecting anti-HAV IgM, while anti-HAV IgG is the major class of antibody generated during the convalescent phase.
Hepatitis A Virus
Hepatitis A virus (HAV) is a nonenveloped virus that belongs to the Hepatovirus genus in the Picornaviridae family. The viral genome consists of a linear, positive-sense, ssRNA that is approximately 7.5 kb in length. HAV demonstrates little antigenic variability, and isolates taken from different parts of the world belong to a single serotype. Acute infection is diagnosed by detecting anti-HAV IgM, while anti-HAV IgG is the major class of antibody generated during the convalescent phase.
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