Simple Molecular Device for Rapid Detection of HSV
Simple Molecular Device for Rapid Detection of HSV
The simple sample work flow recommended in the IsoAmp HSV package insert is a major contributor to its rapid turnaround time, and factors in the cost–effectiveness of the platform for moderate and low-throughput laboratories. The fact that the FDA categorized the IsoAmp HSV test as having a moderate degree of complexity will allow for its implementation in smaller hospitals such that these institutions will no longer have to send HSV testing out to reference laboratories. The analytical sensitivities of a wide range of HDA assays are comparable to those reported for other molecular tests. The use of probes and CIC templates in HDA tests allow for both the moderate multiplex detection of analytes, as well as the detection of nucleic acid amplification inhibitors that are often present in clinical specimens. The aforementioned characteristics make the IsoAmp platform ideal for infrequent tests in sentinel hospitals and clinics that do not want to invest in costly instrumentation.
Conclusion
The simple sample work flow recommended in the IsoAmp HSV package insert is a major contributor to its rapid turnaround time, and factors in the cost–effectiveness of the platform for moderate and low-throughput laboratories. The fact that the FDA categorized the IsoAmp HSV test as having a moderate degree of complexity will allow for its implementation in smaller hospitals such that these institutions will no longer have to send HSV testing out to reference laboratories. The analytical sensitivities of a wide range of HDA assays are comparable to those reported for other molecular tests. The use of probes and CIC templates in HDA tests allow for both the moderate multiplex detection of analytes, as well as the detection of nucleic acid amplification inhibitors that are often present in clinical specimens. The aforementioned characteristics make the IsoAmp platform ideal for infrequent tests in sentinel hospitals and clinics that do not want to invest in costly instrumentation.
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