Efficacy of Infliximab for Refractory Ulcerative Colitis
Efficacy of Infliximab for Refractory Ulcerative Colitis
In conclusion, we found that 64.8% of our patients with refractory UC avoided colectomy by receiving IFX treatment. IFX was more effective when given in combination with thiopurines than when administered as monotherapy. IFX-intensification treatment, however, was required by 70.8% of UC patients. IFX dose should be tailored to individual patients, based on factors baseline serum TNF-α concentration, in the treatment of refractory UC.
Conclusions
In conclusion, we found that 64.8% of our patients with refractory UC avoided colectomy by receiving IFX treatment. IFX was more effective when given in combination with thiopurines than when administered as monotherapy. IFX-intensification treatment, however, was required by 70.8% of UC patients. IFX dose should be tailored to individual patients, based on factors baseline serum TNF-α concentration, in the treatment of refractory UC.
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